پاورپوینت Complement functions

پاورپوینت Complement functions

پاورپوینت Complement functions

                                      

 

 

 

 

 

 

نوع فایل power point

 

قابل ویرایش 51 اسلاید

 

قسمتی از اسلایدها

Proteins of the complement
system (nomenclature)

C1(qrs), C2, C3, C4, C5, C6, C7, C8, C9

factors B, D, H and I,  properdin (P)

mannose binding lectin (MBL), MBL associated serine proteases (MASP-1 MASP-2)

C1 inhibitor (C1-INH, serpin), C4-binding protein (C4-BP), decay accelerating factor (DAF), Complement receptor 1 (CR1), protein-S (vitronectin)

Activation product of complement proteins (nomenclature)

Activated component are usually over-lined: e.g. C1qrs 

When enzymatically cleaved,  the larger moiety, binds to the activation complex or membrane and the smaller peptide is released in the microenvironment

Letter “b” is usually added to the larger, membrane-binding, peptide and “a” to the smaller peptide (e.g., C3b/C3a, C4b/C4a, C5b/C5a), EXCEPT C2 (the larger, membrane-binding moiety is C2a; the smaller one is C2b)

 

فهرست مطالب و اسلایدها

Proteins of the complement
system (nomenclature)

Activation product of complement proteins (nomenclature)

Components of the Classical Pathway

Lytic pathway

Biological Activities of Classical Pathway Components

Control of Classical Pathway Components

Components of mannose-binding lectin pathway

Mannose-binding lectin pathway

Components of the
alternative pathway

Regulation of complement activation

Regulatory mechanisms

انواع مولکولهای کنترلی

C1-Inhibitor       

ممانعت از تشکیل کنورتاز ها

Factor I

مهار تشکیل MAC

Control of spontaneous
C3 activation via CR1

Complement Receptors

Biological effects of C5a

Complement level